A Low level of Melatonin secretion increase the risk of diabetes



A low nocturnal level of melatonin secretion is associated to an higer risk of insurgence of the diabetes kind 2. This is sustained by a research made by the Brigham and Women's Hospital which has highlighted how the quantity of melatonin secreted during the sleep has the capacity to predict the risk of developing diabetes.
The Doctor McMullan, who has coordinated the study published on JAMA, explains: “this is the first time that an association between the secretion of melatonin and the risk of fall il from diabetes 2 has been demonstrated. Now more new investigations will be needed in order to discover how melatonin modifies the glucose metabolism, improving the possibilities of insurgence of diabetes”.

Melatonin is responsible for the sleep-awake cycle and of some effects as the sleepiness and the body temperature lowering. Melatonin also regulates the release of insulin, which regulates the glucose level of blood. These mutations would be the centre of an alteration of the relationship between melatonin and insuline release. So it is about a quite rare series of genetic mutations, but potentially dangerous for the development of the pathology.
During the reaserach 370 women who have developed the diabetes during the follow up and other 370 who were the healty group have been examined. From the results it has emerged that the volunteers whith low levels of melatonin secretion showed twice the prossibilities of fall ill compared with the average.


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